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NOW IS THE TIME

The Alzheimer's Therapeutic Research Institute is the only place in the world doing what we do.  Our researchers have been at this work for decades, and now is a pivotal time in the field to make the greatest impact. 

The scope and scale of our efforts touch every corner of Alzheimer’s and related dementia research.  Collaborative design and open data is at the root of our work, starting with the Alzheimer's Disease Neuroimaging Initiative.  Constant improvement of how we conduct our research to accelerate discoveries is evident in the Alzheimer's Clinical Trial Consortium's we lead.

Helping people affected by  Alzheimer’s and related dementias is our cause.  To rigourously test methods for early detection of and treatments for all stages of Alzheimer's disease and related dementias is our mission.

We advocate for people at highest risk for developing  the disease. We ensure participants' and their families' voices are a meaningful part of our work and that research reaches those who need us most.

Accelerate Scientific Discoveries

The Epstein Family invites you to join the fight to cure Alzheimer’s by making a gift to the USC Epstein Breakthrough Alzheimer’s Research Fund.

For every dollar you give, the Epstein family gives TWO

As an incentive, through the Epstein Alzheimer’s Challenge, they will match your gift two to one to triple the difference you are making.

Daniel J. Epstein Breakthrough Alzheimer’s Research Fund 2023 Awardees

898,539

Total Awarded in 2022
Ralf Langen, Keck School of Medicine and Paul Seidler, School of Pharmacy
CryoEM guided discovery of small molecule inhibitors specific for tau and Aß polymorphs present in Alzheimer’s disease
Paul Seidler, School of Pharmacy and Peter Chung, Dornsife College
Unlocking the Fuzzy Details of Paired Helical Filaments with Phosphorylated Tau
Pinchas Cohen, Davis School of Gerontology and Arthur Toga, Keck School of Medicine
The microprotein SHMOOSE is a new therapeutic candidate for Alzheimer’s disease
Mara Mather, Davis School of Gerontology and Jeiran Choupan, Keck School of Medicine
Effects of Daily Resonance-Frequency Breathing on Brain Perivascular Space Volume

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Saturday, June 14, 2025
San Diego, CA
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