Research
Scientific Papers
Peer-reviewed publications and scientific contributions from the USC Epstein Family Alzheimer’s Therapeutic Research Institute. Explore research that is shaping the understanding, prevention, and treatment of Alzheimer’s disease.
Featured Publications
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May 11, 2026
ATRI Working Paper
Alzheimer’s Clinical Research Data via R Packages: the alzverse
Introducing the alzverse: a suite of R data packages (A4LEARN, ADNIMERGE2) that bundle curated datasets, documentation, and reproducible analysis vignettes from major AD studies into portable, analysis-ready formats to accelerate Alzheimer's research.
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February 23, 2026
The Journal of Prevention of Alzheimer's Disease
Remote outcome measures in Alzheimer’s disease clinical trials: A call to action
An editorial calling for the development and validation of remote outcome measures—smartphone-based cognitive tasks, wearables, speech analytics, and passive sensing—to make Alzheimer's clinical trials more efficient, inclusive, and reflective of real-world patient experience.
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January 26, 2026
Alzheimer's & Dementia
Divergent patterns of cognitive decline in preclinical Alzheimer’s disease: Implications for secondary prevention trials
Latent class analysis of A4 and LEARN data reveals three distinct cognitive trajectories—stable, slow decliners, and fast decliners—among amyloid-positive cognitively unimpaired adults, with major implications for secondary prevention trial design.
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ATRI faculty, staff, and collaborators are encouraged to submit recent publications for inclusion in our scientific papers archive.
Contact atri-info@atri.usc.edu to submit a paper.